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The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene

The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene

Mutant p53 accumulates in cycling and proliferating cells in the normal  tissues of p53 R172H mutant mice
Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice

The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment  of PLK3 | Nature Communications
The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3 | Nature Communications

Synergistic and additive effect of retinoic acid in circumventing  resistance to p53 restoration | PNAS
Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration | PNAS

Figures and data in BAG2 promotes tumorigenesis through enhancing mutant p53  protein levels and function | eLife
Figures and data in BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function | eLife

Mutant p53 expression in various spermatogonia and subset of Leydig... |  Download Scientific Diagram
Mutant p53 expression in various spermatogonia and subset of Leydig... | Download Scientific Diagram

A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic  Activity of p53 - ScienceDirect
A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53 - ScienceDirect

Gain-of-function p53R172H mutation drives accumulation of neutrophils in  pancreatic tumors, promoting resistance to immunotherapy - ScienceDirect
Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy - ScienceDirect

p53_mouse
p53_mouse

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

IJMS | Free Full-Text | Mutant p53 as an Antigen in Cancer Immunotherapy
IJMS | Free Full-Text | Mutant p53 as an Antigen in Cancer Immunotherapy

High metastatic potential in mice inheriting a targeted p53 missense  mutation | PNAS
High metastatic potential in mice inheriting a targeted p53 missense mutation | PNAS

Comparison of Effects of p53 Null and Gain-of-Function Mutations on  Salivary Tumors in MMTV-Hras Transgenic Mice | PLOS ONE
Comparison of Effects of p53 Null and Gain-of-Function Mutations on Salivary Tumors in MMTV-Hras Transgenic Mice | PLOS ONE

The TP53 Website - Mutant TP53 an Oncogene!
The TP53 Website - Mutant TP53 an Oncogene!

Residual apoptotic activity of a tumorigenic p53 mutant improves cancer  therapy responses | The EMBO Journal
Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses | The EMBO Journal

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in  Pancreatic Cancer - ScienceDirect
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer - ScienceDirect

Frontiers | Mutant p53: Multiple Mechanisms Define Biologic Activity in  Cancer
Frontiers | Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer

GOF p53 interacts with Med17 and amino acid acids at mouse p53 L25, W26...  | Download Scientific Diagram
GOF p53 interacts with Med17 and amino acid acids at mouse p53 L25, W26... | Download Scientific Diagram

Addgene: Lox-stop-Lox p53 R172H
Addgene: Lox-stop-Lox p53 R172H

Biomolecules | Free Full-Text | Advanced Strategies for Therapeutic  Targeting of Wild-Type and Mutant p53 in Cancer
Biomolecules | Free Full-Text | Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer

Crippling p53 activities via knock-in mutations in mouse models | Oncogene
Crippling p53 activities via knock-in mutations in mouse models | Oncogene

Mutant p53 accumulates in cycling and proliferating cells in the normal  tissues of p53 R172H mutant mice. - Abstract - Europe PMC
Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice. - Abstract - Europe PMC

Mutant p53 accumulates in cycling and proliferating cells in the normal  tissues of p53 R172H mutant mice. - Abstract - Europe PMC
Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice. - Abstract - Europe PMC

The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene